Unlock the Secrets of He Shou Wu: Your Guide to Polygonum Multiflorum Extract

If you work with natural ingredients—for cosmetics, health supplements, or pharmaceuticals—you’ve probably heard of Polygonum multiflorum extract. Also known as Fo-Ti extract, this natural ingredient comes from a traditional Chinese herb and gains more popularity worldwide. But what exactly is it? How do we test its quality? And how to use it properly? 

Today, we break down all the key details in simple terms, so you can use this ingredient with confidence!

What Exactly is Polygonum Multiflorum Extract?

Polygonum multiflorum extract comes from the root of Polygonum multiflorum, also known as He Shou Wu in traditional herbal practice. Manufacturers process the dried root through water or ethanol extraction, then concentrate and dry it into powder form.
The main active components include:
Stilbene glycosides (especially 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside, often used as a marker compound)
Anthraquinones (such as emodin and physcion)
Phospholipids
Tannins
Flavonoids
Among these, stilbene glycosides serve as the primary quality control indicator in most commercial specifications.

How Do We Test Polygonum Multiflorum Extract?

Testing ensures the extract’s quality, safety and effectiveness. We use 3 simple, reliable methods for daily checks:
HPLC: The most common method to quickly and accurately measure key components like TSG and emodin.
UV-Vis Spectrophotometry: Simple and fast for testing total polysaccharide content.
MEKC: Ideal for water extracts, separating and detecting multiple bioactive components at once.
All tests focus on two key goals: ensuring sufficient active components and keeping harmful substances within safe limits.

Application Scenarios Based on Different Concentrations

Different extract ratios and active content levels suit different industries. Here is a practical breakdown:

  • Low Concentration (e.g., 10:1 extract powder):Functional teas,Health beverages,Traditional herbal formulas,General wellness supplements
  • Medium Standardized Content (e.g., 10%–20% stilbene glycosides):
    Capsules and tablets,Nutraceutical blends,Anti-aging supplements
  • High Standardized Content (e.g., 50%+ stilbene glycosides):Premium nutraceutical products,High-end cosmetic formulations,Research and development applications

Solubility and Appearance

These two points are key for formula design. Let’s keep it simple:
Color: Usually brown to yellowish-brown powder. Shade varies by extraction method and concentration (darker with higher concentrations), safe and barely affects final product appearance.
Solubility: Dissolves well in water and 50% aqueous ethanol, slightly soluble in pure ethanol, insoluble in oil. Mixes easily in water-based products; add a solubilizer for oil-based ones.
 
Storage: Keeping the Power Intact
 
Polygonum multiflorum extract is sensitive to its environment. To maintain its potency for its full 24-month shelf life, follow these simple rules:

Seal it tight: Use air-tight containers to prevent moisture absorption (it is hygroscopic!).
Stay cool and dry: Store in a cool area away from direct sunlight.
Avoid metal: Whenever possible, use food-grade plastic liners or fiber drums to prevent any trace mineral reactions.

Final Thoughts

Polygonum multiflorum extract is more than just a trend; it is a versatile, science-backed ingredient that bridges the gap between nature and beauty. Whether you are creating a revolutionary hair care line or a high-end supplement, this extract offers the bioactive punch your customers are looking for.

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